밤마다 모든 것이 살아나는 뉴욕 자연사 박물관. 야간 경비원 ‘래리’(벤 스틸러)는 대통령 ‘테디 루즈벨트’(로빈 윌리엄스), 카우보이 ‘제레다야’(오웬 윌슨), 말썽꾸러기 원숭이 ‘덱스터’ 등 매일 밤 살아나는 전시물들과 함께 판타스틱한 박물관 재개장 전야 이벤트를 개최한다. 하지만 점차 마법의 기운을 잃어 가는 황금석판으로 인해 다시는 살아나지 못할 위기에 처한 그들은 황금석판의 비밀을 밝혀내기 위해 영국 런던 대영박물관으로 향하는데...
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Ben Stiller
Larry Daley / Laaa
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Robin Williams
Theodore Roosevelt
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Owen Wilson
Jedediah Smith
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Steve Coogan
Octavius
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Ricky Gervais
Dr. McPhee
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Dan Stevens
Sir Lancelot
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Rebel Wilson
Tilly
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Skyler Gisondo
Nick Daley
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Rami Malek
Ahkmenrah
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Patrick Gallagher
Attila the Hun
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Mizuo Peck
Sacajawea
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Ben Kingsley
Merenkahre
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Dick Van Dyke
Cecil
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Mickey Rooney
Gus
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Bill Cobbs
Reginald
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Andrea Martin
Rose
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Rachael Harris
Madeline Phelps
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Matt Frewer
Archibald Stanley
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Brad Garrett
Easter Island Head (voice)
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Regina Taufen
New York Reporter (voice)
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Percy Hynes White
C.J. Fredericks
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Brennan Elliott
Robert Fredericks
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Kerry van der Griend
Neanderthal #1
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Matthew Harrison
Neanderthal #2
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Jody Racicot
Neanderthal #3
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Randy Lee
Hun #1
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Darryl Quon
Hun #2
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Paul Chih-Ping Cheng
Hun #3
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Anjali Jay
Shepseheret
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Matty Finochio
Roman Sentry
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Patrick Sabongui
Amir
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Amir M. Korangy
1938 Egyptian Worker
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Louriza Tronco
Andrea
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Sophie Levy
Sophie
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Jin Sangha
Egyptian High Priest
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James Neate
Augustus Statue
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Alice Eve
Alice Eve (uncredited)
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Hugh Jackman
Hugh Jackman (uncredited)
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James M.L. Muller
Theatre Patron (uncredited)
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Dmitrious Bistrevsky
Greek Statue (uncredited)
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Steve Saunders
Passerby (uncredited)
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Michael Denis
Young Ahkmenrah's Father (uncredited)
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Theo Devaney
Lord Nelson (uncredited)
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Nils Hognestad
Cowboy (uncredited)
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Craig March
NY Cop (uncredited)
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Martyn Mayger
Action Car Driver (uncredited)
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Jacqueline Ryan
Wealthy Donor (uncredited)
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Ella Olivia Stiller
Child on London Bus (uncredited)
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Seth Whittaker
Museum Guard (uncredited)
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Crystal the Monkey
Dexter
